Many Stroke Patients Stop Taking Meds

(August 10, 2010) - Researchers say there is no one reason, but many people who suffer a stroke (Read about "Stroke") endanger their lives by stopping some or all of their medications. A quarter of stroke patients discontinue one or more of their prescribed secondary stroke prevention medications within three months of hospitalization for an acute stroke, according to a report posted online in the Archives of Neurology, one of the JAMA/Archives journals.

Each year, there are an estimated 180,000 recurrent strokes in the United States, according to background in the article. "Reducing the rate of recurrent stroke requires detecting and treating modifiable risk factors in the early post-stroke period and developing strategies to improve patient persistence with medication regimens," the authors add.

The authors studied 2,598 patients 18 years or older who had been admitted to 106 U.S. hospitals with ischemic stroke or transient ischemic attack. Patients were asked a series of standardized questions regarding their medication use three months after hospital discharge. Those reporting continued use of a therapy or class of therapies from hospital discharge through three months were described as "persistent."

The authors found that, "of those treated, 75.5 percent were persistent with all the medications prescribed by their physician." Additionally, further analysis showed that nearly 20 percent of patients were taking at least half of their prescribed medications, while 3.5 percent of patients were taking none of their medications at three months.

Multiple factors were associated with persistence in continuing secondary medication regimens including the presence of cardiovascular disease and risk factors prior to stroke, having insurance, being prescribed fewer discharge medications and having an understanding of why these medications were prescribed and how to refill prescriptions. Additionally, increasing age, lesser stroke disability and financial hardship were also associated with persistence in continuing medication regimens.

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